Scientific Programme

Thursday 23rd September 2010

11.00 – 13.00 Registration for meeting and hotels plus a light lunch

13.00 Welcome and Conference Overview (Jo Bradwell, Birmingham, UK)

13.05 – 14.30 Review lectures
Chair: Jo Bradwell

13.05 The Monoclonal Proteins: A Brief History (Bob Kyle, Mayo Clinic, USA)
13.35 Serum Free Light Chain (sFLC) guidelines for monoclonal gammopathies (Brian Durie, Cedars-Sinai, USA)
13.55 Serum FLC assay: Technical considerations (Hugh Carr-Smith, Birmingham, UK)
14.10 Role of sFLC assays in the laboratory (Jerry Katzmann, Mayo Clinic, USA)

14.30 Coffee / Tea

15.00 – 16.00 Free light chains (FLCs) and the kidney
Chair: Paul Cockwell

15.00 Use of high cut-off haemodialysis for the treatment of myeloma kidney: Worldwide experience to date (Colin Hutchison, Birmingham, UK)
15.20 EuLITE Trial: results to date (Mark Cook, Birmingham, UK)
15.45 Polyclonal FLC and Chronic Kidney Disease (Stephanie Stringer, Birmingham, UK)
16.00 – 19.00 Poster Session: Wine and cheese reception

Friday 24th September 2010

09.00 Poster prizes announcements

09.10 - 10.50 Diseases associated with monoclonal free light chains
Chair: Bob Kyle

09.10 AL amyloidosis – Role of FLC assay in risk estimation (Shaji Kumar, Mayo Clinic, USA)
09.30 FLCs in the amyloidosis clinic (Philip Hawkins, London, UK)
09.50 Serum Free Light Chains in Chronic Lymphocytic Leukaemia (Guy Pratt, Birmingham, UK)
10.10 Serum Free Light Chains in Non-Hodgkin Lymphoma (Matthew Maurer / Thomas Witzig USA)
10.30 Progressing serum immune abnormalities in myelomagenesis (Ola Landgren, Bethesda, USA)

10.50 Coffee / Tea

11.15 – 12.40 Diseases associated with elevated polyclonal free light chains I
Chair: Philip Hawkins

11.15 Concepts (Graham Mead, Birmingham, UK)
11.35 Non-clonal serum immunoglobin free light chains (FLC) as markers of overall survival (Angela Dispenzieri, Mayo Clinic, USA)
12.00 Polyclonal free light chain elevation and mortality in the German Heinz Nixdorf Recall study (Jan Dürig, Essen, Germany)
12.20 Circluating serum free light chains as predictors of AIDS lymphoma and beyond (Ola Landgren, Bethesda, USA)

12.40 – 13.40 Lunch

13.40 – 14.40 Diseases associated with elevated polyclonal free light chains II
Chair: Angela Dispenzieri

13.40 Hepatitis C and lymphoma development (Benjamin Terrier, Paris, France)
14.00 Free light chains of immunoglobulins as disease activity markers in autoimmune diseases (JE Gottenberg, Paris, France)
14.20 Clinical and biological relevance of serum Free Light Chains (sFLC) assessment in patients with Hodgkin's lymphoma (Antonio Pinto, Naples, Italy)

14.40 Coffee / Tea

15.00 - 17.00 Hevylite
Chair: Jo Bradwell, Bob Kyle, Brian Durie

15.00 Concepts (Jo Bradwell, Birmingham, UK)
15.20 Diagnostic role of Heavy / Light Chain Analysis (Stephen Harding, Birmingham, UK)
15.40 Monitoring multiple myeloma patients with heavy / light chain antibodies for IgA and IgG (Heinz Ludwig, Vienna, Austria)
16.00 Prognostic role of myeloma (Hérve Avet-Loiseau, Nantes, France)
16.20 Prognostic role of Hevylite in MGUS (Jerry Katzmann, Mayo Clinic, USA)
16.40 Case studies (Graham Mead, UK)

17.00 Summary and close (Jo Bradwell, UK, Bob Kyle, USA, Brian Durie, USA)

19.00 Drinks Reception at the Roman Baths followed by Conference Dinner